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       2025-10-08 16:43:38 
   
      
           
      
           
                        
          hotspot  
          
                                   
                 
                                      author：comprehensive   
                                        
                                      
                                      Page View：49
                                  
                                    
          
                                   
          translucent 3D DNA helix with blue and purple background
          Adobe
          Verve Therapeutics said Monday that it had received clearance from the Food and Drug Administration to conduct a clinical trial in the U.S. of its experimental, gene-editing treatment for a common form of heart disease.
          The FDA’s action removes a clinical hold on Verve’s CRISPR-based therapy, called VERVE-101, that was placed on it last November. Verve now intends to recruit participants from U.S. sites into a Phase 1 study that’s been underway since last year in New Zealand and the United Kingdom.
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          “We’re thrilled to get this clearance for VERVE-101,” said Verve CEO Sek Kathiresan. “Our study is called HEART-1 and our plan now is to activate U.S. sites.”
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